Quickly attain sections as skinny or thick as your application necessitates, devoid of worrying about dropping or distorting important tissue samples.
Megatome is really a vibrating microtome meant to portion a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With large blade vibrating frequency and minimized blade deflection, Megatome enables superior-throughput tissue sectioning with uniform floor profile, together with minimum tissue injury and data reduction.
Antibodies may possibly just take months to diffuse via just a few millimeters of tissue, that has a steep labeling gradient from area to core.
Megatome is made for accuracy: the blade vibrates at a greater frequency and larger amplitude variety than other microtomes, and features a distinctive deflection control mechanism.
SE uses a rotational electric field to disperse highly electromobile molecules (which include antibodies or surfactant micelles) all over a porous sample devoid of detrimental electrically charged structures within the tissue. This allows two-4 day clearing of intact organs,
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Megatome is actually a novel microtome that enables for top-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimum tissue destruction and data loss.
eFLASH is often a fast tissue labeling system that permits for uniform whole-organ staining in twenty rounds of labeling.
The SmartSPIM light sheet microscope supplies unparalleled resolution and acquisition speed in the course of intact tissue volumes, whilst its modular structure megatomi.com permits you to enhance and personalize unique elements.
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Defend avoids the variability of hydrogel embedding and the data loss from PFA preservation, defending specimens for many rounds of processing.
Leverage the Distinct+ tissue clearing approach, in conjunction with eFLASH and patented stochastic electrotransport systems, to quickly distinct and label whole organs. Critical highlights and characteristics consist of:
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